Search on: ACETOLACTATE SYNTHETASE 
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Descriptor English:   Acetolactate Synthase 
Descriptor Spanish:   Acetolactato Sintasa 
Descriptor Portuguese:   Acetolactato Sintase 
Synonyms English:   Acetohydroxyacid Synthetase I
Acetoxyhydroxyacid Synthase III
Acid Synthase, Acetohydroxy
Acid Synthetase, Acetohydroxy
Synthase III, Acetoxyhydroxyacid
Synthase, Acetohydroxy Acid
Synthase, Acetolactate
Synthetase I, Acetohydroxyacid
Synthetase, Acetohydroxy Acid
Synthetase, Acetolactate
Acetohydroxy Acid Synthetase
Acetohydroxy Acid Synthase
Acetolactate Synthetase  
Tree Number:   D08.811.913.200.324
D12.776.331.049
Definition English:   A flavoprotein enzyme that catalyzes the formation of acetolactate from 2 moles of PYRUVATE in the biosynthesis of VALINE and the formation of acetohydroxybutyrate from pyruvate and alpha-ketobutyrate in the biosynthesis of ISOLEUCINE. This enzyme was formerly listed as EC 4.1.3.18. 
History Note English:   91(75); was see under KETOACID-LYASES 1975-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   100 
Unique Identifier:   D000095 

Occurrence in VHL: 		 

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